The question you ask is simple, but unfortunately the answer may be quite complex. In order to get accurate simulation results you need to setup the simulation so that it mimics what you have in real life as closely as possible. Seemingly small details can make the results completely wrong. I'm not even remotely an expert in simulation but I've messed with it enough to know that it can be very tricky. So I make no guarantees on the soundness of my advice on this. How's that for confidence boosting?
LOL ! I'll take whatever advice you have and trust it !
Ok, so first I have a few questions.
Are you trying to test the C channels or just the thin plate?
The plate, do determine the thinnest we can use.
Are the C channels rigidly attached to the floor, or are they able to slide? (bolted, welded, etc.?)
These 6" channels are welded to 8" channels below them. The space between the 6" channels is fully occupied by other equipment keeping the addition of other structural members from being place there and the height has been specified so we can't add structural members on top of the 6" channels so must rely on the plate for support.
Are the C channels rigidly attached to the thin plate, or can the plate slide? (bolted, welded, etc.?)
The plate will be welded to the 6" channels.
Does the thick plate that you're using to represent the weight of the machine,
Yes represent what the bottom of the machine is actually like?
No Meaning is the bottom of the machine a flat area the same size as the thick plate? Or does the machine have feet? If the machine does have feet, the placement of the feet on the thin plate will have a significant impact on the deflection.
The machine actually has a rectangle c-channel sub-frame with the same footprint as the steel block I'm modeling that will set on the plate.
Is the machine rigidly attached to the thin plate?
The machine's sub-frame will be bolted to the plate.
What version of Solidworks do you have, and are you using the full simulation package or just simulation express? If you have the full package you can run the simulation as an assembly and possible get more realistic results, but the setup is more complicated. Given that what (I think) you're trying to figure out is relatively simple, an assembly is probably not needed. I ask what version of SW you have because if it's 2013 or newer I can put a simple example together and post it. Though if you have a student version that may also be an extra complication, I'm not sure.
It's 2014 full and have been trying to run the full simulation on the assembly.
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