I would imagine that the major disadvantage would be the cost of the assembly. Two aluminum timing pulleys, belt, bearing with set screws in the collar, and a brass nut from Roton. You can fix the ends however you want, I chose to use two more nuts so that I could tension the leadscrew..
Not seeing a lot of racking, I intend to use a "mayline" approach to eliminating all racking. Like a drafting ruler.