After having to put up with my criticisms of a lot of your designs, now is your chance to weigh in on one of mine! The idea is to build a sizeable, fairly heavy-duty and versatile CNC router which could either mount a spindle directly and a table to work in 3-axis mode, work in 4-axis mode with the table removed, or have a swiveling/tilting head fitted to work in 5 or 6 axis mode.
The idea is to weld up four 4-foot sections of 12"x 12" square pipe with base-plates so that these units can be bolted to the floor. They would be filled with concrete so that each one would have four sections of one-inch threaded rod sticking up. Some 10-foot lengths of heavy steel tubing 4" x 8" with a 3/8" wall thickness would be drilled to accept these rods, and then precisely leveled with nuts and washers. Then each one of them would have epoxy cast on top to provide a flat surface to mount 20mm profile rails.
On the side of each tube a piece of aluminum with a shoulder milled into it would be mounted and carefully shimmed to be straight and parallel to the one on the other side. This would have sections of Nexen rack attached to it, so it could be driven on both sides at once with roller-pinion wheels, a system that's supposed to eliminate backlash and the other inefficiencies of rack-and-pinion drives.
On top of these rails, a gantry built from two 72" lengths of 4" x 4" x 1/4" wall stainless steel tubing with an aluminum backing plate to unify them will ride on ball-bearing trucks. Between these tubes, a ball screw will transmit motion to the Z axis, rolling on a set of 15mm square profile rails. The Z axis will provide about 30" of travel, powered by a harmonic-drive servo actuator, and will itself be a linear actuator with internal ballscrew and profile rails. The spindle will either be attached directly to this actuator or to a B/C axis head which would provide the other 2 degrees of motion, powered also by harmonic-drive servo actuators.
The 4th axis would be a commercial rotary table, and the tailstock would be repurposed from a lathe.
This design is still in progress - there are lots of things I haven't figured out yet, like what's driving all these different servos, whether it's all powered by servos or some steppers should be used, whether to use a commercial control or build my own from a breakout board and individual drivers, how exactly I'm going to get everything to line up perfectly in all dimensions - but I figured it was far enough along to ask for feedback from my pals here in the Zone. So don't hold back - tell me what you really feel.