I regularly trepan large diameter through holes (3"-4.25" diameter) in 1/2" thick aluminum plate using a 1/2" 2-flute high helix endmill programmed using G2 and depth of cut increments of 0.1" and plenty of flood coolant. The finish cut is done with a boring head and CCGT carbide inserts. See:
http://i72.photobucket.com/albums/i1...blankFlynn.jpg I suppose that if the endmill was not long enough to trepan 1.5" thick aluminum then one could trepan half way through and flip the part to trepan the other half through. On my manual mill and manual lathe I use an SPI Val-Cut 8mm "dragcut" trepanning tool but since getting the Tormach it is way easier to program an end mill to do the trepanning. Here is a picture of the Val-Cut trepanning tool in use on my manual lathe
http://i72.photobucket.com/albums/i1...repanning2.jpg BTW I don't use flood cooling on the manual lathe or mill but a Vortec model 610 cold air gun when trepanning. The flood coolant on the Tormach is much better than the Vortec cold air gun but flood cooling on a manual machine makes quite a mess.
Don